Scientific + Clinical Advisers.
Mario L. Suvà MD, PhD
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Associate Professor of Pathology at Mass General Hospital and Harvard Medical School
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Director, Molecular Pathology Unit
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Vice Chair, Research, Dept of Pathology at Mass General Hospital
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Robert B. Colvin, MD, Endowed Chair in Pathology
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Institute Member at the Broad Institute of MIT and Harvard
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Co-Director, Cancer Program, Harvard Stem Cell Institute
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Co-Leader, DF/HCC Neuro-Oncology Program
Mario Suvà is the Director of the Molecular Pathology Unit and Vice-Chair for Research in the Department of Pathology at Massachusetts General Hospital (MGH). Suvà’s expertise is in neuro-oncology, single-cell genomics and chromatin analysis.
Suvà’s laboratory focuses on brain tumours, both in adults and children. A particular effort of the laboratory is on dissecting the heterogeneity of diffuse gliomas and relating transcriptional and genetic programs of individual cancer cells.
Suvà directed landmark studies characterising glioblastoma, oligodendroglioma, astrocytoma, pediatric gliomas and medulloblastoma with single-cell genomic and spatial genomic technologies, shedding light on tumor heterogeneity, tumor classification, glioma cell lineages, cancer stem cell programs, tumour evolution and the composition of the tumour microenvironment.
Suvà obtained his Ph.D. in Lausanne, Switzerland, studying cancer stem cells in gliomas and sarcomas. He earned his M.D. from the University of Lausanne and his certification in Neuropathology from the Swiss Medical Association. He did his post-doctoral research at MGH and the Broad Institute, applying chromatin analysis and functional approaches to identify master regulators of glioma stem cell programs.